Product Information：
- Product name: LORAPLAZ Pralsetinib 25mg
- Manufacturer / brand: Laos Alliance
- Active ingredient: Pralsetinib
- Current strength: 100mg
- SKU: 05-L-1102
- Site category: RET target, RET target in thyroid cancer, other cancer
Active Ingredient and Reference Data
Pralsetinib is the active ingredient used for this product page. Public prescribing information for Pralsetinib was used for the medical reference sections. Medical details are provided for reference and must be interpreted by a qualified healthcare professional.
Mechanism of Action
Pralsetinib is a kinase inhibitor of wild-type RET and oncogenic RET fusions (CCDC6- RET ) and mutations ( RET V804L, RET V804M and RET M918T) with half maximal inhibitory concentrations (IC 50s ) less than 0.5 nM. Certain RET fusion proteins and activating point mutations can drive tumorigenic potential through hyperactivation of downstream signaling pathways leading to uncontrolled cell proliferation.
Storage and Purchase Notes
Store according to the package or pharmacist instructions and keep out of reach of children. Before ordering, confirm product name, strength, quantity, price, shipping details, and payment method. After receipt, check packaging, batch number, expiration date, and storage conditions.
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