Product Information：
- Product name: LORAPLAZ Lorlatinib 100mg
- Manufacturer / brand: Laos Alliance
- Active ingredient: Loratinib
- Current strength: 100mg
- SKU: 03-L-0956
- Site category: broad-spectrum anticancer drugs, NTRK target, other cancer
Active Ingredient and Reference Data
Loratinibis the active ingredient used for this product page. Public prescribing information for Loratinibwas used for the medical reference sections. Medical details are provided for reference and must be interpreted by a qualified healthcare professional.
Mechanism of Action
Lorlatinib competitively inhibits the kinase activity of ALK/ROS1 through a large ring structure, blocking downstream carcinogenic pathways such as PI3K/AKT and RAS/MAPK. At the same time, it overcomes drug resistance mutations such as G1202R and efficiently penetrates the blood-brain barrier. It is currently the third-generation ALK inhibitor with the broadest resistance spectrum and the strongest efficacy in treating brain metastases.
Storage and Purchase Notes
Store according to the package or pharmacist instructions and keep out of reach of children. Before ordering, confirm product name, strength, quantity, price, shipping details, and payment method. After receipt, check packaging, batch number, expiration date, and storage conditions.
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