Product Information：
- Product name: Sotorasib 120mg
- Manufacturer / brand: Laos Alliance
- Active ingredient: Pretomanid
- Current strength: 120mg
- SKU: 06-L-0981
- Site category: KRAS G12C target, other cancer
Active Ingredient and Reference Data
Sotorasib is the active ingredient used for this product page. Public prescribing information for Sotorasib was used for the medical reference sections. Medical details are provided for reference and must be interpreted by a qualified healthcare professional.
Mechanism of Action
Sotorasib is an inhibitor of KRAS G12C, a tumor-restricted, mutant-oncogenic form of the RAS GTPase, KRAS. Sotorasib forms an irreversible, covalent bond with the unique cysteine of KRAS G12C, locking the protein in an inactive state that prevents downstream signaling without affecting wild-type KRAS. Sotorasib blocked KRAS signaling, inhibited cell growth, and promoted apoptosis only in KRAS G12C tumor cell lines. Sotorasib inhibited KRAS G12C in vitro and in vivo with minimal detectable off-target activity.
Storage and Purchase Notes
Store according to the package or pharmacist instructions and keep out of reach of children. Before ordering, confirm product name, strength, quantity, price, shipping details, and payment method. After receipt, check packaging, batch number, expiration date, and storage conditions.
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