【us：Tabrecta】Alliance CAPANIB Capmatinib 200mg/tablet 56tablets/bottle

Product Information：

• Product name: CAPANIB Capmatinib 200mg
• Manufacturer / brand: Laos Alliance
• Active ingredient: Capmatinib
• Current strength: 200mg
• SKU: 09-L-1381
• Site category: general medicines, MET target

Active Ingredient and Reference Data

Capmatinib is the active ingredient used for this product page. Public prescribing information for Capmatinib was used for the medical reference sections. Medical details are provided for reference and must be interpreted by a qualified healthcare professional.

Mechanism of Action

Capmatinib is a kinase inhibitor that targets MET, including the mutant variant produced by exon 14 skipping. MET exon 14 skipping results in a protein with a missing regulatory domain that reduces its negative regulation leading to increased downstream MET signaling. Capmatinib inhibited cancer cell growth driven by a mutant MET variant lacking exon 14 at clinically achievable concentrations and demonstrated anti-tumor activity in murine tumor xenograft models derived from human lung tumors with either a mutation leading to MET exon 14 skipping or MET amplification.

Storage and Purchase Notes

Store according to the package or pharmacist instructions and keep out of reach of children. Before ordering, confirm product name, strength, quantity, price, shipping details, and payment method. After receipt, check packaging, batch number, expiration date, and storage conditions.