Product Information：
- Product name: Selpercatinib 40mg
- Manufacturer / brand: Laos Alliance
- Active ingredient: Selpercatinib
- Current strength: 40mg
- SKU: 11-L-1233
- Site category: RET target, RET target in thyroid cancer, other cancer
Active Ingredient and Reference Data
Selpercatinibis the active ingredient used for this product page. Public prescribing information for Selpercatinibwas used for the medical reference sections. Medical details are provided for reference and must be interpreted by a qualified healthcare professional.
Mechanism of Action
Selpercatinib is a kinase inhibitor. Selpercatinib inhibited wild-type RET and multiple mutated RET isoforms as well as VEGFR1 and VEGFR3 with IC 50 values ranging from 0.92 nM to 67.8 nM. Certain point mutations in RET or chromosomal rearrangements involving in-frame fusions of RET with various partners can result in constitutively activated chimeric RET fusion proteins that can act as oncogenic drivers by promoting cell proliferation of tumor cell lines.
Storage and Purchase Notes
Store according to the package or pharmacist instructions and keep out of reach of children. Before ordering, confirm product name, strength, quantity, price, shipping details, and payment method. After receipt, check packaging, batch number, expiration date, and storage conditions.
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